Which mutation could be passed on to future generations?

A. A nerve cell has an adenine substituted for a guanine base on one of its chromosomes

B. A strand of mRNA has a mistake in it that was not in the original DNA strand

C. A sperm cell has an extra nucleotide on chromosome 23 that was not in the parent cell

D. A strand of replicated DNA in a liver cell has a mistake on it that wasn’t in the original DNA strand