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Explain how these individuals can carry a fusion gene that is transcriptionally active and yet do not develop CML.

Explain how these individuals can carry a fusion gene that is transcriptionally active and yet do not develop CML.

CML is actually developing in a latent form.
A single gene alteration is not the only requirement for CML.
Developing CML after the gene fusion can take a long time.
None of the above

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