Eishehdanago Eishehdanago Biology Answered PLEASE HELP EMERGENCY!! IF YOU ARE NOT 100% SURE ABOUT YOUR ANSWER DO NOT ANSWER THEN!! PLEASE!! Question: What is the difference between an organ and a tissue? an organ is made up of less cells than a tissue organs are a group of cells that make up tissues tissues are not made up of cells, organs are made up of cells tissues are a group of cells that make up organs (This is 7th grade science)