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Answer :

[tex]\displaystyle\ \boxed{a^m\cdot a^n=a^{m+n}}\\\\4^{3c} \cdot 4^{5c}=\frac{4}{16} \\\\4^{3c+5c}=4^{-1}\\\\8c=-1\\\\c=-\frac{1}8}[/tex]

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