By the remainder theorem, the remainder upon dividing a polynomial [tex]p(x)[/tex] by a linear factor [tex]x - c[/tex] is exactly [tex]p(c)[/tex].
Then the remainder upon dividing [tex]f(x)[/tex] by [tex]x - 4[/tex] is
[tex]f(4) = 3\times4^3 + 5\times4^2 + 5 = \boxed{277}[/tex]
