Answer :
Activators and repressors change the relationship of RNAP II to the transcription complex and DNA loops bring distant enhancer or silencer elements in proximity with promoter regions of the genes.
How does activators and repressors influence the rate of transcription initiation?
Transcription boost transcription of genes. Repressors decrease the transcription. Groups of transcription factors binding the sites that are called enhancers and silencers can turn a gene on/off in specific parts of the body.
Activators and repressors regulate transcription in eukaryotes by interacting with general transcription factors and other components of the transcriptional machinery and also by inducing changes in the structure of chromatin.
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